NLA Releases an Update on Lp(a)

Two key takeways:
- Lp(a) is considered a continuous independent risk factor, not dichotomous.
- Recognition of 3 levels of risk and recommendation to re-measure in patients with intermediate-risk levels.
- Low risk: Lp(a) levels below 75 nmol/L (30 mg/dL).
- Intermediate risk: Lp(a) levels between 75 and 125 nmol/L (30-50 mg/dL).
- High risk: Lp(a) levels equal to or above 125 nmol/L (50 mg/dL). These risk classifications are used to assess the risk of atherosclerotic cardiovascular disease (ASCVD) events and guide treatment decisions. It is important to note that these risk classifications are specific to Lp(a) levels and should be interpreted in the context of a patient’s overall cardiovascular risk profile. The intermediate risk category is sometimes referred to as the “gray zone” and may warrant repeat measurement. These risk categories apply across races and ethnicities.
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