Outlast everything else — the science of cardiovascular longevity.
Cardiovascular disease is not inevitable aging — it is accelerated vascular aging driven by identifiable, modifiable risk factors. The science of cardiovascular longevity is the science of keeping those drivers under control long enough for your heart to outlast everything else.
All longevity guides
This guide series covers the testing, metrics, and interventions that matter most for cardiovascular longevity — beyond standard cholesterol panels and blood pressure readings. Written and reviewed by Dr. Regina Druz, MD, MBA, FACC, FMCP-M, whose clinical work focuses on root-cause cardiovascular risk assessment and precision cardiology.
Vascular Age
How to measure your true cardiovascular age with CAC, CIMT, and VO2 max — and the evidence-based interventions that actually lower it.
VO2 Max and Heart Health
Why VO2 max is the strongest predictor of cardiovascular longevity — and what interventions actually raise it.
Heart Rate Variability
HRV as a window into autonomic nervous system health — how to measure it, interpret it, and improve it.
CIMT Testing
Carotid intima-media thickness as an early-detection tool — who should get it, what the numbers mean, and what to do next.
Coronary Calcium Score
Why the CAC score is the single most powerful predictor of future cardiac events — and how to act on your result.
Genetic Testing for Heart Disease Risk
What genomic testing reveals about inherited cardiovascular risk — Lp(a), APOE, factor V Leiden, and polygenic risk scores explained.
Hormone Therapy and Heart Risk
A nuanced look at hormone replacement therapy and cardiovascular outcomes — the timing hypothesis, therapy type, and who benefits.

