What Is Endothelial Dysfunction? The Earliest Warning Sign of Heart Disease — and How to Reverse It
Heart DiseaseVascular Aging Medically reviewed by Dr. Regina Druz, MD, MBA, FACC, FMCP-M — Integrative Cardiologist, Holistic Heart Centers · Last updated: June 2026 Endothelial dysfunction is one of the earliest measurable changes in the cardiovascular system — a shift in the thin lining of your blood vessels that begins years, sometimes decades, before plaque, a blockage,…