Your Heart Risk Is Not Your Destiny.

Holistic Heart Centers is a premiere integrative cardiology practice — finding and fixing the root causes your standard checkup misses.

  • Board-Certified Cardiology
  • Longevity Medicine
  • Genomic Testing
  • HeartWell® AI
  • New York-based
  • Telehealth Nationwide

Most cardiology practices manage heart disease. At Holistic Heart Centers, we reverse it — using genomics, advanced biomarker testing, and personalized protocols built around your specific biology.

The Gap In Standard Care

Your Cardiologist Said You’re ‘Fine.’ But Something Feels Wrong.

Standard cardiology is excellent at treating heart disease once it’s advanced. But it was not designed to find the underlying causes before that happens — inflammation, insulin resistance, genetic vulnerabilities, hormone imbalances, sleep disorders, gut dysfunction.

Your standard cholesterol panel misses Lp(a) — a genetic lipid marker present in 1 in 5 people that dramatically increases heart attack risk and is not treated by statins. Your standard stress test tells you whether your arteries are blocked today, not whether they’re quietly calcifying. Your annual checkup does not measure the biomarkers that predict cardiovascular risk 10 to 20 years before an event.

This is not a failure of your cardiologist. It is a limitation of the standard model. Holistic Heart Centers was built because that model was not enough.

There is a different approach. It starts with a different question. Instead of asking ‘Is your heart sick?’ we ask: ‘Why is your heart at risk — and what specifically can we do about it, for you?’

Founded by Dr. Regina Druz, MD, MBA, FACC, FMCP-M — integrative cardiologist, cardiac imaging researcher, functional medicine specialist, and nationally recognized expert — HHC was built on a simple premise: heart disease has root causes that standard cardiology rarely investigates, and finding them changes everything.

Holistic Heart Centers is the only practice in the New York area transforming cardiology from problem to prevention, using functional medicine, genomic risk profiling, and AI-powered cardiovascular assessment — designed to find and address root causes before symptoms appear.

The HHC Difference

Three principles behind every protocol.

Principle 01

Root-Cause Diagnostics

HHC uses advanced biomarker panels, genetic risk profiling, and advanced vascular imaging to find what standard testing misses. Every care plan starts with real data about your specific biology.

Principle 02

Functional + Conventional

We combine the advancements of conventional cardiology with the depth of functional medicine. You get safe and personalized care — this is the insight of integrative medicine, positioned to work for you.

Principle 03

Powerful & Personalized

Your cardiovascular risk is more than a population metric. It is shaped by your genetics and vascular biology. Our HeartWell® AI risk engine translates your risk into a protocol built for your biology — and Fit in Your GENES® delivers it.

The HeartWell System

How The HeartWell® System Works — Your Three-Step Journey

Step 1

Explore

Know your real numbers beyond the standard panel.

Your HeartWell® Toolkit arrives at home. A simple fingerstick sample or blood draw measures the advanced biomarkers your annual physical skips — Lp(a), hs-CRP, homocysteine, cardiovascular genetic markers, hormone levels, and metabolic indicators. You receive a report or review everything in a 45-minute physician visit.

Start with Step 1
Step 2

Deep Dive

Find the root causes, not just the risk factors.

Based on your results, our clinical team builds a comprehensive picture of your cardiovascular biology: inflammation pathways, insulin resistance patterns, hormonal dynamics, genetic variants affecting lipid metabolism, gut microbiome markers, longevity trajectory. Every finding maps to a specific, evidence-based intervention, tracked with HeartWell® AI.

Learn about Step 2
Step 3

Engage

A personalized protocol. Ongoing support. Measurable results.

Your Fit in Your GENES® program is a structured, supervised protocol addressing the specific root causes identified in your Deep Dive — diet, genomics, stress physiology, sleep, targeted supplementation, and precision medication management where appropriate. Progress is tracked. Protocols are adjusted. Results are measured. Decisions are guided by data, not influencers.

Learn about Step 3

Not sure which step is right for you? Take the 3-minute HeartWell® Quiz and get a personalized recommendation.

Take the HeartWell® Quiz

What We Treat

Integrative Cardiology for the Conditions That Matter Most

Holistic Heart Centers takes an integrative approach to cardiovascular conditions that conventional medicine often undermanages — especially where genetics, hormones, metabolism, and lifestyle interact in complex ways. If you have been told to ‘watch and wait,’ there is likely more that can be done.

Measurable outcomes. Not just managed conditions.

1500+
Patients treated
17
Peer-reviewed publications
39+
Podcast episodes
25+
Years integrative cardiology

What patients say about Holistic Heart Centers

Meet Dr. Regina Druz, MD, MBA, FACC, FMCP-M

Dr. Regina Druz, MD, MBA, FACC, FMCP-M
Dr. Regina Druz, MD, MBA, FACC, FMCP-M

Dr. Druz is a board-certified cardiologist, functional medicine specialist, and the founder of Holistic Heart Centers. She has authored 17 peer-reviewed publications, trained at leading academic medical centers, and built HHC to offer patients a level of cardiovascular investigation that standard cardiology does not provide.

Her patients come from across the country — by telehealth and in person on Long Island — to access a level of cardiovascular care that does not exist in most hospitals.

Meet Dr. Druz

From the Own Your Heart Health Podcast

Dr. Druz and expert guests explore integrative cardiology, functional medicine, longevity and heart disease prevention — with the science behind every recommendation.

Own Your Heart Health with Dr. Regina Druz EP41: Inflammation, ImmunGLP-1 Microdosing & Hormonal Optimization in Perimenopause

Ep. 42: Small Dose, Big Power: Microdosing GLP-1 to Quell Midlife Inflammation — with Dr. Jennifer Roelands, Integrative Gynecologist

Own Your Heart Health Podcast with Dr. Regina Druz, MD
Own Your Heart Health with Dr. Regina Druz
Ep. 42: Small Dose, Big Power: Microdosing GLP-1 to Quell Midlife Inflammation — with Dr. Jennifer Roelands, Integrative Gynecologist
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Guest: Dr. Jennifer Roelands, MD — Integrative Gynecologist & Longevity Physician In this episode, Dr. Regina Druz is joined by Dr. Jennifer Roelands — a board-certified OB-GYN who practices integrative gynecology and longevity medicine — to reframe GLP-1 agonists (semaglutide and tirzepatide) as a form of hormonal replacement therapy rather than simple weight-loss drugs. They...

Listen Now →

At-Home Testing

Know Your Heart Health Numbers.
From Home.

The HeartWell® Toolkit is an at-home blood and genetics test that measures the advanced biomarkers your annual physical doesn’t include — the markers that predict cardiovascular risk years before standard tests show a problem.

Fingerstick or venous collection, urine and saliva. The most comprehensive biomarker collection for heart health and longevity.

Measures: Lp(a) · hs-CRP · Homocysteine · Insulin resistance markers · Hormone panel · Genetic cardiovascular variants · Epigenetic age markers

HSA/FSA eligible.

Sample HeartWell® Toolkit results report showing heart age and advanced biomarkers

Patient Stories

Real results from HeartWell® Toolkit patients.

Outcomes from patients who started with an at-home HeartWell® Toolkit and built a plan with Dr. Druz.

Nick, 49
Nick, 49Heart & Brain Toolkit
★★★★★
I eat well and exercise, but my cholesterol stayed high. Eight months later — without medication — Dr. Druz had found exactly what was driving my lipids and built a protocol that worked.
  • LDL ↓49%
  • Total cholesterol ↓40%
  • Triglycerides <100
Lidia, 58
Lidia, 58Hormones & Metabolism Kit
★★★★★
After menopause my inflammation rose and my Lp(a) was flagged. My old cardiologist said to watch it. Dr. Druz found why it was rising and built a plan for both.
  • hsCRP normalized
  • Lp(a) stabilized
Sheldon, 50
Sheldon, 50Longevity Kit
★★★★★
After my heart attack I was told to take meds and watch my diet. Dr. Druz ran the full longevity panel, found every residual risk driver, and gave me a real protocol.
  • 25 lbs lost
  • BP normalized
  • Vascular age stabilized

Holistic Heart University — a heart health community that goes deep.

Dr. Druz’s free educational community for patients, caregivers, and the heart-curious. Get the monthly heart-health newsletter, the full searchable archive, peer discussion, and early access to new guides and HeartWell® Toolkits — written for patients, not physicians.

Join Holistic Heart University →

Long Island & New York City. And Wherever You Are.

In-Person

55 Bryant Avenue, Suite #6, Roslyn, NY 11576

240 West 37th St, 5th floor, New York, NY 10018

By Appointment Only: 877-511-5166

Locations & Directions

Telehealth

Available in all 50 states.

No travel required.

Same comprehensive care, anywhere.

Speak With a Human

Your heart history is not your heart destiny.

Find out what your standard tests are missing.

Free 30-minute discovery call. By phone or video. · Telehealth patients in all 50 states welcome.

Frequently Asked Questions

What is an integrative cardiologist and how are they different from a regular cardiologist?+

An integrative cardiologist combines board-certified cardiovascular medicine with functional medicine, genomics, and lifestyle medicine to find and treat the root causes of heart disease rather than just managing symptoms. At Holistic Heart Centers, we use advanced biomarker testing — including genetic cardiovascular markers, Lp(a), inflammatory markers, and metabolic panels — to identify why each patient’s heart is at risk, then build a personalized prevention and treatment protocol around that specific biology.

Can I see a physician at Holistic Heart Centers if I don’t live on Long Island?+

Yes. Holistic Heart Centers provides comprehensive integrative cardiology consultations via telehealth to patients in all 50 states. Telehealth patients begin with the at-home HeartWell® Toolkit — a blood and genetics test that ships to your home — and complete their initial physician visit via secure video call. All follow-up visits and program support are available remotely.

Can heart disease actually be reversed?+

Research shows that specific components of cardiovascular disease — including arterial inflammation, insulin resistance, and early-stage atherosclerotic plaque progression — can be meaningfully reduced through targeted lifestyle, nutritional, and metabolic interventions. The integrative approach uses genomic and biomarker testing to identify which root causes are driving each patient’s disease, then designs interventions precisely targeted at those causes.

What happens on my first visit at Holistic Heart Centers?+

Your first visit is a 30-minute physician consultation — delivered via telehealth — in which our clinical team reviews your HeartWell® Toolkit results or your own labs, your health history, and your specific cardiovascular concerns. We explain what your advanced biomarker results mean, identify the root causes most relevant to your situation, and outline the specific integrative protocol we recommend for you.