New Cholesterol Guidelines 2026: LDL Targets, Lp(a), and What Changed

The 2026 ACC/AHA Dyslipidemia Guideline introduces five major changes: a new risk calculator (PREVENT replaces Pooled Cohort Equations), explicit LDL targets reinstated (below 55 mg/dL for highest-risk patients), universal Lp(a) testing for every adult, formal Class 3 (No Benefit) ratings for dietary supplements, and CAC score tiers tied directly to LDL goals. This article explains [...]

By |2026-05-23T20:17:43+00:00May 23rd, 2026|

Glycocalyx…Hype or Hope?

I started looking into Glycocalyx. Several presenters recently implied that it may be a worthwhile target for modification. While there is an extensive body of research supporting the Glycocalyx role of vascular repair, blood pressure, brain, heart, kidney health, and microvasculature regulation, I find the lack of clinical outcome with supplementation troubling. The data is [...]

By |2025-03-25T19:11:38+00:00February 20th, 2025|